Association between ACTN3 gene polymorphism and muscle strength in older adults

Journal of Education, Health and Sport

卷:8

Walery Zukow¹  Marcin Kożuchowski²  Dominika Gębka²  Joanna Androsiuk-Perkowska²  Radosław Perkowski²  Marta Podhorecka²  Kornelia Kędziora-Kornatowska²  Sławomir  Kujawski³  Henryk Kozłowski⁴  Sylwester Kłoska⁴  Anna Marciniak⁴  Marcin Woźniak⁴ 

[1] Department of Spatial Management and Tourism,Faculty of Earth Sciences,Nicolaus Copernicus University in Torun, Torun;

[2] Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń;

[3] Faculty of Health Sciences, Department of Hygiene, Epidemiology and Ergonomics, Division of Ergonomics and Exercise Physiology, Nicolaus Copernicus University in Toruń;

[4] Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń;

关键词: sport geneticsł actn3ł older adultsł geriatric patient;   

DOI  :  10.5281/zenodo.1345234

来源: DOAJ

【 摘 要 】

The decrease of muscle strength and general physical fitness is a big problem in the elderly group. It often prevents the proper functioning of a person, which makes him/her dependent on caretakers. It is believed that the some polymorphisms in ACTN3 geneare associated with better results in strength sports. If those polymorphisms affect muscle strength, they may also be related to the health condition of older people. Our study was conducted on a group of 60 people over 60 years of age. The relationship between overall fitness and muscular strength of elderly patients with ACTN R577X gene polymorphism was checked. The ACTN3 gene was tested by PCR-RFLP. Overall fitness was tested using the IPAQ questionnaire and fitness tests: Tinetti, DGI, Up&Go, SPPB, standing on one leg (both right and left). Based on the results of the survey, the MET and BMI coefficients were determined. It was found that the RX genotype is associated with better results achieved in the SPPB test. Genotype XX was associated with worse results in the right leg standing test (p

【 授权许可】

Unknown