Option B plus antiretroviral therapy adherence and associated factors among HIV positive pregnant women in Southern Ethiopia

BMC Pregnancy and Childbirth

卷:19

Kaleegziabher Lukas¹  Ermias Abera Turuse¹  Fanuel Belayneh Bekele²  Dawit Jember Tesfaye²  Feleke Tafesse Asfaw³  Abraham Abate Altaye⁴  Desalegn Tsegaw Hibistu⁵  Teshome Abuka Abebo⁵  Tariku Laelago⁶  Henok Gebreyohaness Kebede⁷ 

[1]College of Medicine and Health Sciences, Wachemo University

[2]|Department of Epidemiology, School of Public Health, College of Medicine and Health Sciences, Hawassa University

[3]|Department of Health Service Management, School of Public Health, College of Medicine and Health Sciences, Hawassa University

[4]|Department of Midwifery, Hawassa College of Health Sciences

[5]|Department of Reproductive Health, School of Public Health, College of Medicine and Health Sciences, Hawassa University

[6]|Hossana College of Health Sciences

[7]|Yale Global Leadership Institute, Yale School of Public health

关键词: Antiretroviral therapy;    Adherence;    Option B plus;    Pregnant women;   

DOI  :  10.1186/s12884-019-2228-4

来源: DOAJ

【 摘 要 】

Abstract Background Adherence to Option B plus Antiretroviral Therapy plays a vital role in preventing mother to child transmission of Human Immunodeficiency Virus and development of drug resistance. This study was aimed to assess adherence to option B plus ART and associated factors among HIV positive pregnant women at public Hospitals in Southern Ethiopia. Methods Facility based cross sectional study was conducted on HIV positive pregnant mothers attending public health facilities’ antenatal care unit. Systematic random sampling technique was employed to select 290 HIV positive pregnant women enrolled in the Option B plus program. Data were collected by using structured questionnaire. Bivariate and multivariable logistic regression analysis were used to identify factors associated with option B plus ART adherence. P-value less than 0.05 was considered as cut of point to declare statistical significance. Results The overall adherence to option B plus ART among HIV positive pregnant women was 236 (81.4%). Three in twenty, (14.8%) participants were none adherent to Option B plus ART due to difficulty in adopting time schedule and forgetting to take medication. During first trimester of pregnancy, 16 (5.5%) were stopped taking ART medication due to side effects. Pregnant women who started ART at the time of HIV diagnosis [AOR = 1.99, 95% CI: (1.02, 3.95)], and who had five or more antenatal care visits [AOR = 4.10, 95% CI (1.65, 10.02)] were more likely to adhere to option B plus ART. Women who should travel 30–60 min on foot to access ART from service delivering facilities were less likely to adhere to option B plus [AOR = 0.39, 95% C I: (0.17, 0.88)]. Conclusions The overall adherence to option B plus ART was suboptimal. Measures that improve recalling ability of individuals to take ART on time, and minimize ART side effects during first trimester of pregnancy need to be given emphasis. The study finding indicates the need for reconsidering the ad-hoc focused antenatal care visit at policy and program level by increasing the number of follow up visit with proper counseling on ART adherence benefits, and improving service accessibility.

【 授权许可】

Unknown