An Alternative Method for Generating Arynes fromortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether

Molecules

卷:20

Yuki Hazama¹  Yuto Sumida¹  Takahisa Yano¹  Suguru Yoshida¹  Takamitsu Hosoya¹ 

[1] Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering,Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan;

关键词: aryne;    ortho-silylaryl triflate;    cesium carbonate;    crown ether;   

DOI  :  10.3390/molecules200610131

来源: DOAJ

【 摘 要 】

An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied toa variety of reactions between several arynes and arynophiles. We also demonstrated that the efficiency of aryne generation is significantly affected by the alkali metal countercation of the carbonate.

【 授权许可】

Unknown