Enalapril microhemodynamic effects in patients with essential arterial hypertension

Российский кардиологический журнал

卷:0

Z. A. Baste¹  S. P. Oransky¹  A. Yu. Blednova¹  Z. A. Avakimyan¹  L. N. Eliseeva¹ 

[1] Кубанская государственная медицинская академия;

关键词: hypertension;    enalapril;    indapamide;    endothelin-1;    microcirculation;   

DOI  :  

来源: DOAJ

【 摘 要 】

The study included 38 patients with essential arterial hypertension (EAH), Stage I-II, and 10 healthy individuals (control group). Microcirculation was assessed by laser Doppler flowmetry (IDF), endothelin-1 concentration - by immunoenzyme assay. In EAH patients, microcirculation was heterogeneous, with the prevalence of pathological static type. Enalapril was an effective and safe antihypertensive medication, beneficial for microcirculation system. Serum endothelin-1 concentration correlated with systolic blood pressure (BP), as well as with IDF endothelial activity.

【 授权许可】

Unknown