A Case Report of Blood Group Discrepancy because of Anti A1 with Clinical Significance and Anti C

Medical Laboratory Journal

卷:6

J Esmaeili¹  P Babadivand¹  P Ebrahimy¹  M Selseleh¹ 

[1] ;

关键词: anti c and anti a1 with clinical importance;    pnh;    ab screening;   

DOI  :  

来源: DOAJ

【 摘 要 】

AbstractBackground and objectives: ABO phenotyping is one of the essential tests in Immunohematology. Incompatible blood group transfusion leads to acute hemolysis reactions and other serious complications. Anti A1 is a cold Antibody with no clinical significance, but if it is reacted at 37˚c can be clinically significant, which will be happened rarely. At the present, we report a Case with anti A1 having clinical significance and Anti C.Material and methods: The patient was suffering from Paroxysmal nocturnal hemoglobinuria (PNH) and received repeated blood transfusion. The tests performed for this patient were blood grouping, Antibody screening, panel test and cross match.Result:the patient’s blood group is AB (A2B) with anti A1.The presence of anti C is verified by applying Panel test. Conclusion: to prepare appropriate blood, Cross mach test was performed on A2B blood bags without C Antigen. During laboratory tests and blood transfusion, no reaction was observed. This report indicates that being aware of anti-antigen antibodies is an important point.Key words: Anti C and Anti A1 with Clinical importance, PNH, Ab Screening

【 授权许可】

Unknown