The role of central reading centers - current practices and future directions

Indian Journal of Ophthalmology

卷:63

关键词: Community;    digital imaging;    Karnataka Internet-assisted Diagnosis of Retinopathy of Prematurity;    retinopathy of prematurity;    telemedicine;    universal screening;    Age-related macular degeneration;    en-face optical coherence tomography;    polypoidal choroidal vasculopathy;    Choroid;    enhanced depth imaging technique;    swept source optical coherence tomography;    Choroidal imaging;    choroidal thickness;    retinal dystrophies;    Choroidal neovascularization;    idiopathic juxtafoveal telangiectasis;    juxtafoveal retinal telangiectasia;    lutein;    macular edema;    macular pigment;    macular telangiectasia;    Müller cells;    parafoveal telangiectasis;    perifoveal telangiectasis;    retinal angiomatous proliferation;    retinal telangiectasis;    subretinal neovascularization;    zeaxanthin;    Microscope-integrated optical coherence tomography;    RESCAN;    spectral domain optical coherence tomography;    vitreoretinal surgery;    Central reading center;    randomized controlled trial;    standard operating procedure;   

DOI  :  10.4103/0301-4738.159866

来源: DOAJ

【 摘 要 】

Central reading centers (CRCs) have several crucial roles in the conduct of clinical trials, providing key input during the study design, preparation of the operations manual, as well as site and photographer certification. They provide objective, standardized grading of images from study subjects, which determines study eligibility, and also evaluate lesion features at subsequent study visits. CRCs need to adhere strictly to Good Clinical Practice (GCP) guidelines, as well as the established standard operating procedures in order to ensure that images are graded properly. The role of CRCs will continue to evolve, and include the use of web-based image transmission and grading platforms.

【 授权许可】

Unknown