The Phenotype Paradox: Lessons From Natural Transcriptome Evolution on How to Engineer Plants

Frontiers in Plant Science

卷:11

Justin Law¹  Oliver P. F. Windram¹  Kangbo Ng² 

[1] Grand Challenges in Ecosystems and the Environment, Imperial College London, Ascot, United Kingdom;

[2] Institute for the Physics of Living Systems, University College London, London, United Kingdom;

[3] The Francis Crick Institute, London, United Kingdom;

关键词: directed evolution;    gene network analysis;    synthetic biology;    systems biology;    breeding and genomics;   

DOI  :  10.3389/fpls.2020.00075

来源: DOAJ

【 摘 要 】

Plants have evolved genome complexity through iterative rounds of single gene and whole genome duplication. This has led to substantial expansion in transcription factor numbers following preferential retention and subsequent functional divergence of these regulatory genes. Here we review how this simple evolutionary network rewiring process, regulatory gene duplication followed by functional divergence, can be used to inspire synthetic biology approaches that seek to develop novel phenotypic variation for future trait based breeding programs in plants.

【 授权许可】

Unknown