Mood Disorder in Cancer Patients Undergoing Radiotherapy During the COVID-19 Outbreak

Frontiers in Psychology

卷:12

Angelo Sangiovanni¹  Alfonso Reginelli¹  Salvatore Cappabianca¹  Roberta Grassi¹  Michele Caraglia¹  Maria Angela Polifrone²  Pierpaolo Correale²  Claudia Vinciguerra³  Cesare Guida⁴  Angela Di Biase⁴  Valerio Nardone⁴  Maria Grazia Calvanese⁴  Sara Falivene⁴ 

[1] Department of Precision Medicine, University of Campania “Luigi Vanvitelli,” Naples, Italy;

[2] Unit of Medical Oncology, Grand Metropolitan Hospital “Bianchi Melacrino Morelli,” Reggio Calabria, Italy;

[3] Unit of Neurology, University Hospital of Salerno, Salerno, Italy;

[4] Unit of Radiation Oncology, Ospedale del Mare, Naples, Italy;

关键词: mood disorders;    COVID-19;    radiotherapy;    cancer;    anxiety;    depression;   

DOI  :  10.3389/fpsyg.2021.568839

来源: DOAJ

【 摘 要 】

Introduction: Novel coronavirus (COVID-19) is having a devastating psychological impact on patients, especially patients with cancer. This work aims to evaluate mood disorders of cancer patients undergoing radiation therapy during COVID-19 in comparison with cancer patients who underwent radiation therapy in 2019.Materials and Methods: We included all the patients undergoing radiation therapy at our department in two-time points (once a week for a month in May 2019) and during the COVID-19 outbreak (in April 2020). All the patients were asked to fulfill a validated questionnaire (STAI-Y1, State trait anxiety inventory scale), the Symptom Distress thermometer (SDT) (from 0 to 10 score), and the Beck Depression Inventory v.2 (BDI-2). We took into account the COVID-19 outbreak and also sex, age, week of radiation treatment, and disease.Results: We included 458 patients (220 males and 238 females), with a median age of 64 years. STAI-Y1 median score was 40 (mean 41,3, range 19–79), whereas the median score of SDT was five and BDI-2 median score was 11. STAI-Y1, SDT, and BDI-2 were significantly correlated with the COVID-19 outbreak (p < 0,001 for all the tests), sex (p: 0,016 for STAI-Y1, p < 0.001 for SDT, p:0.013 for BDI-2), week of treatment (p: 0.012 for STAI-Y1 and p: 0.031 for SDT), and disease (p:0.015 for STAI-Y1, p < 0.001 for SDT and p:0.020 for BDI-2).Conclusions: The prevalence of mood disorders in patients undergoing radiation therapy is higher than expected and even higher during the COVID-19 outbreak. These measurements could be useful as a baseline to start medical humanities programs to decrease these scores.

【 授权许可】

Unknown