Assessment of blood metabolism under the subchronic influence to singlet oxygen in experiment

Кубанский научный медицинский вестник

S. P. Peretyagin¹  A. G. Soloveva¹ 

[1] Federal state budgetary institution «Privolzhsky federal research medical centre» of the Ministry of health of the Russian Federation;

关键词: синглетный кислород;    кровь;    лактат;    глюкоза;    оксидоредуктазы;    singlet oxygen;    blood;    lactate;    glucose;    oxidoreductase;   

DOI  :  10.25207/1608-6228-2016-1-134-137

来源: DOAJ

【 摘 要 】

The metabolic characteristics of blood of animals following subchronic exposure of gaseous mixtures containing singlet oxygen were investigated. The experiment was carried out on Wistar rats. In the blood the concentration of glucose, lactate, the activity of catalase, aldehyde dehydrogenase, lactate dehydrogenase were determined after 30 and 60 days after externally-inhalation. It is shown that prolonged use for 30 days gas mixture containing singlet oxygen, increases the detoxification function and antioxidant reserve of erythrocytes, decreases the concentration of glucose in blood, leading to reduction of the coefficient of energy reaction balance and the accumulation of lactate in erythrocytes. Long-term results (60 day) of externally-inhalation of a gas mixture containing singlet oxygen, reveal a violation of energy metabolism blood normalizing the specific activity of aldehyde dehydrogenase and increasing the catalase of erythrocytes, increasing concentration of glucose in blood.

【 授权许可】

Unknown