Antimicrobial Actions and Applications of Chitosan

Polymers

卷:13

Fu-Sheng Deng¹  Chih-Yu Chuang¹  Cai-Ling Ke¹  Ching-Hsuan Lin¹ 

[1] Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei 10617, Taiwan;

关键词: chitosan;    antimicrobial activity;    physicochemical characteristics;    nanoparticles;    films;   

DOI  :  10.3390/polym13060904

来源: DOAJ

【 摘 要 】

Chitosan is a naturally originating product that can be applied in many areas due to its biocompatibility, biodegradability, and nontoxic properties. The broad-spectrum antimicrobial activity of chitosan offers great commercial potential for this product. Nevertheless, the antimicrobial activity of chitosan varies, because this activity is associated with its physicochemical characteristics and depends on the type of microorganism. In this review article, the fundamental properties, modes of antimicrobial action, and antimicrobial effects-related factors of chitosan are discussed. We further summarize how microorganisms genetically respond to chitosan. Finally, applications of chitosan-based biomaterials, such as nanoparticles and films, in combination with current clinical antibiotics or antifungal drugs, are also addressed.

【 授权许可】

Unknown