Interatrial block and atrial remodeling assessed using speckle tracking echocardiography

BMC Cardiovascular Disorders

卷:18

Roberto Elosua¹  Carima Belleyo-Belkasem²  María Manuela Izquierdo-Gómez²  Patricia Barrio-Martínez²  Juan Lacalzada-Almeida²  Antonio Bayés de Luna³  Luis Alberto Escobar-Robledo³  Alejandro Jiménez-Sosa⁴  Javier García-Niebla⁵ 

[1] Cardiovascular Epidemiology and Genetics Research Group, IMIM (Hospital del Mar Medical Research Institute);

[2] Department of Cardiology, Hospital Universitario de Canarias;

[3] Fundación Investigación Cardiovascular, Institut Català Ciències Cardiovasculars;

[4] Research Unit, Hospital Universitario de Canarias;

[5] Servicios Sanitarios del Área de Salud de El Hierro, Valle del Golfo Health Center;

关键词: Interatrial block;    Speckle tracking echocardiography;    Strain;    Strain rate;    Left atrium;   

DOI  :  10.1186/s12872-018-0776-6

来源: DOAJ

【 摘 要 】

Abstract Background To evaluate the possibility of left atrial (LA) remodeling using speckle tracking echocardiography (STE) in patients with interatrial block (IAB). Methods We performed a cross-sectional study with three groups of patients: 56 without IAB, 21 with partial IAB (pIAB), and 22 with advanced IAB (aIAB). Transthoracic echocardiographic (TTE) STE was performed and clinical and echocardiographic findings were analyzed. Results TTE showed higher LA volume/body surface area in the patients with IAB. With STE, the absolute value of strain rate during atrial booster pump function (SRa) and early reservoir period (SRs) decreased in the pIAB group and even more in the aIAB group, compared to the group without IAB. The independent variables were the echocardiographic measures of LA size and function. After adjusting for confounders, both multiple linear regression and multivariate multinomial regression showed good correlation with dependent variables: longer P-wave duration on electrocardiography and with the type of IAB, respectively. SRa (p < 0.001), SRs (p < 0.001), and maximal peak LA longitudinal strain in the reservoir period (p = 0.009) were independently associated with P-wave duration. SRa was also associated with the presence of pIAB (OR = 11.5; 95% confidence interval (CI): 2.7–49.0; p = 0.001) and aIAB, (OR = 98.2; 95% CI: 16–120.4; p < 0.001) and SRs was associated with pIAB (OR: 0.03; CI: 0.003–0.29; p = 0.003) and with aIAB (OR: 0.008; CI: 0.001–0.12; p = 0.004). Conclusions IAB correlates directly with structural remodeling and a decrease in the absolute value of LA SRa and SRs determined using STE.

【 授权许可】

Unknown