期刊论文详细信息
Journal of Contemporary Medicine 卷:11
Botulinum toxin A in Patients with Chronic Migraine: A Single-Center Experience;
Şükran Çevik Yurtoğulları1 
[1] GAZİLER FİZİK TEDAVİ REHABİLİTASYON EĞİTİM VE ARAŞTIRMA HASTANESİ;
关键词: baş ağrısı;    kronik migren;    botilinum toksin a;    baş ağrısı;    kronik migren;    botilinum toxin a;   
DOI  :  10.16899/jcm.821703
来源: DOAJ
【 摘 要 】

Abstract:Objective : The Botulinum toxin A (BoNT/A), increasingly used in many fields in recent years, was shown to be effective in chronic migraine (CM) in recent studies. In this study, we aimed to investigate treatment response in our CM patients who underwent BoNT/A therapy.Methods: The study included 41 CM patients (aged 18-65 years). We questioned patients undergoing BoNT/A therapy regarding demographic characteristics, education level, time of diagnosis, migraine triggers, and previous therapies at first visit prior to injection. Thepatients were assessed together with analgesic use, visual analog scale (VAS) score and Migraine Disability Assessment Score (MIDAS) rating at month 6 after treatment.Results: There were 36 women (87.8%) and 5 men (12.2%) in the study group. Mean age was calculated as 44.88±10.51 years. Of the patients, 20 patients (48.8%) fulfilled criteria for migraine with aura while no aura was detected in 21 patients (51.2%). Significant decrease was detected in MIDAS rating and VAS scores after BoNT/A therapy (p<0.001).Conclusion: The BoNT/A was found to be effective and safe in the prophylactic treatment of chronic migraine. The BoNT/A is a potent treatment that could be performed by experienced neurologists in eligible CM patients regardless of previous prophylactic treatments.

【 授权许可】

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