Efficacy of Selective Laser Trabeculoplasty in Phakic and Pseudophakic Patients with Open-Angle Glaucoma

Siriraj Medical Journal

卷:69

Sakaorat Petchyim¹  Naris Kitnarong¹  Chutima Wongsiwaroj² 

[1] Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University;

[2] Thainakarin Hospital;

关键词: Selective laser trabeculoplasty;    efficacy of selective laser trabeculoplasty;    pseudophakic eye;    pseudophakia (Siriraj Med J 2017;    69: 70-74);   

DOI  :  10.14456/smj.2017.14

来源: DOAJ

【 摘 要 】

Objective: To compare the efficacy of selective laser trabeculoplasty (SLT) in terms of intraocular pressure (IOP)reduction between phakic and pseudophakic patients with open-angle glaucoma (OAG).Methods: Phakic and pseudophakic patients with OAG who had IOP ≥15 mmHg treated with ≥2 topical antiglaucomamedications were enrolled. Pseudophakic eyes with history of complicated phacoemulsification wereexcluded. SLT was performed 270 degrees by one surgeon under the same protocol. IOP was measured withapplanation preoperatively and at 1 hour, 1 week, 3 weeks and 3 months postoperatively.Results: There were 59 eyes (38 phakia and 21 pseudophakia) from 38 patients enrolled between September 2011and August 2012. The mean IOP significantly decreased from 19.5±2.5 and 20.2±3.2 mm Hg preoperatively to15.6±3.4 and 15.3±3.1 mm Hg postoperatively at 3 months in phakic and pseudophakic group respectively. MeanIOP reduction was not significantly different between phakic (3.9± 3.1 mmHg) and pseudophakic group (5.0±3.06mmHg, p=0.197). The non-inferiority test indicated that mean IOP reduction in pseudophakic group was noninferiorto phakic group (p=0.012).Conclusion: SLT was effective for IOP reduction in both phakic and pseudophakic eyes with OAG. The efficacy ofSLT in pseudophakic eyes was not inferior to phakic eyes.

【 授权许可】

Unknown