Inflammatory glaucoma. Elements of etiology and pathology

The Moldovan Medical Journal

卷:63

Liliana Groppa¹  Vitalie Cusnir²  Valeriu Cusnir Jr²  Valeriu Cusnir²  Lilia Dumbraveanu²  Nicolae Bobescu² 

[1] Department of Internal Medicine, Rheumatology and Nephrology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova;

[2] Department of Ophthalmology and Optometry, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova;

关键词: inflammatory glaucoma;    uveitic glaucoma;    secondary glaucoma;   

DOI  :  10.5281/zenodo.4016822

来源: DOAJ

【 摘 要 】

Background: Inflammatory glaucoma, also known as uveitic glaucoma is a multifactorial process of inflammation that causes the rising of intraocularpressure (IOP) accompanied by morphological and physiological modifying similar to open angle glaucoma. The mechanisms by which ocular inflammationcauses an increase of the IOP are not integrally comprehended, and many of the relevant pathways and features are still covered with a veil of mystery.The eyes of uveitic patients are defined by complex interactions between the angles (open or closed), trabecular outflow, fluctuations in the aqueousproduction and the response to steroids. Regarding the elevation of IOP in these individuals, it is mostly attributed to the increased outflow resistance,which distorts the equilibrium between aqueous production and outflow.Conclusions: Inflammatory glaucoma is a multifactorial pathology that needs a careful diagnosis and therapeutical approach in order to obtain a goodmanagement of inflammatory process and intraocular pressure. There are a lot of pathological pathways that influence the evolution of inflammatoryglaucoma and make treatment more difficult. Last years, glaucoma treatment has significantly improved, but to better understand pathogenesis of uveiticglaucoma more scientific studies are necessary.

【 授权许可】

Unknown