Baclofen in the short-term maintenance treatment of benzodiazepine dependence

Journal of Neurosciences in Rural Practice

卷:05

Arun Kandasamy¹  Vivek Benegal¹  Lekhansh Shukla¹  Muralidharan Kesavan¹ 

[1]Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India

关键词: anti-craving;    baclofen;    benzodiazepines;    dependence;    gamma-aminobutyric acid b;    maintenance;   

DOI  :  10.4103/0976-3147.145203

来源: DOAJ

【 摘 要 】

Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.

【 授权许可】

Unknown