Kinetics of the reaction of 5-substituted orotic acids with diazodiphenylmethane

Journal of the Serbian Chemical Society

卷:69

关键词: orotic acids;    diazodiphenylmethane;    reaction kinetics dimethylformamide;   

DOI  :  

来源: DOAJ

【 摘 要 】

Rate konstants for the reaction of eight 5-substituted orotic acids with diazodiphenylmethane (DDM) in dimethylformamide (DMF) were determined at 30 ºC by the known spectrophotometric method. The determined rate constants were correlated with the equations:log k2 = as1 + bsR + hlog k2 = as1 + bsR + yn + hto detect the presence and investigate the influence of both electrical and steric substituent effects. The obtained results show that the electrical effect (the localized – field and delocalized – resonance) is predominant and that the steric effect, althought present, is releatively small in this reaction.

【 授权许可】

Unknown