Audiological follow-up of children with congenital Zika syndrome

Heliyon

卷:8

Rebeka J.F. Maciel¹  Ângela C. Leão²  Vanessa Van Der Linden³  Enny S. Paixão³  Silvio S. Caldas⁴  Elizabeth B. Brickley⁵  Marli T. Cordeiro⁶  Gabriella G.S. Leitão⁶  Danielle S. Ramos⁷  Lilian F. Muniz⁷  Kátia M.G. Albuquerque⁷  Mariana C. Leal⁷ 

[1] Corresponding author.;

[2] Universidade Católica de Pernambuco, Brazil;

[3] Agamenon Magalhães Hospital, Brazil;

[4] Aggeu Magalhães Research Center, Oswaldo Cruz Foundation, Brazil;

[5] Barão de Lucena Hospital, Brazil;

[6] London School of Hygiene and Tropical Medicine, Department of Infectious Disease Epidemiology, United Kingdom of Great Britain and Northern Ireland;

[7] Universidade Federal de Pernambuco, Brazil;

关键词: Zika virus;    Congenital infection;    Congenital Zika syndrome;    Microcephaly;    Birth defects;    Hearing loss;   

DOI  :  

来源: DOAJ

【 摘 要 】

How does the auditory function of children with congenital Zika syndrome present during the first three years of life? To determine the auditory function of children with congenital Zika syndrome during the first three years of life and estimate the frequency and long-term presentation of hearing loss in this syndrome, an auditory assessment with screening and diagnostic tests was conducted. The screening test consisted of measuring the short latency ABR using click stimuli. If the ABR click indicated hearing loss, confirmation was obtained with a frequency-specific ABR (FS-ABR), in which the stimuli were tone bursts at frequencies of 500 and 2000 Hz by bone and air conduction. This case series included 107 children with confirmed congenital Zika syndrome, and the cumulative incidence of sensorineural hearing loss in the first three years of life was 9.3% (10/107). There were no cases of delayed-onset or progressive deficits in hearing. Early presentation of sensorineural hearing loss seems to occur with a higher frequency in children with congenital Zika syndrome than in the general population. Sensorineural hearing loss resulting from congenital Zika virus infection does not appear to present with delayed onset or with progressive deficits.

【 授权许可】

Unknown