Sertoli–Leydig cell tumor of the ovary: A diagnostic dilemma

Gynecologic Oncology Reports

卷:15

Casandra A. Liggins¹  Ly T. Ma²  Matthew P. Schlumbrecht³ 

[1] Department of Obstetrics and Gynecology at Banner University Medical Center, Phoenix, AZ, USA;

[2] Department of Pathology, Banner MD Anderson Cancer Center, Gilbert, AZ, USA;

[3] Gynecologic Oncology, Division of Surgery, Banner MD Anderson Cancer Center, Gilbert, AZ, USA;

关键词: Sertoli–Leydig;    Sex-cord;    Carcinoid;    Hepatoid;    Alphafetoprotein;    Endometrioid;   

DOI  :  10.1016/j.gore.2015.12.003

来源: DOAJ

【 摘 要 】

Background: Sertoli–Leydig cell tumors are rare sex-cord stromal tumors of the ovary that can present with a variety of histological elements, which may complicate diagnosis and treatment.Case: A 40-year-old female presenting with pelvic pain is found to have a large complex right adnexal mass and elevated alpha-fetoprotein. The mass was diagnosed as a Sertoli–Leydig cell tumor with heterologous elements including carcinoid and hepatoid components. She was treated with surgical resection followed by adjuvant chemotherapy and remains clear of disease.Conclusion: Prognostic indicators for Sertoli–Leydig cell tumors include degree and type of heterologous element differentiation. Thorough characterization of such elements is crucial for adequate diagnosis and treatment.

【 授权许可】

Unknown