Special Issue: Application of Extracellular Matrix in Regenerative Medicine

Applied Sciences

卷:11

NeillJ. Turner¹ 

[1] McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA;

关键词: extracellular matrix;    scaffold;    wound healing;    regenerative medicine;    tissue engineering;    decellularization;   

DOI  :  10.3390/app11073262

来源: DOAJ

【 摘 要 】

The present Special Issue comprises a collection of articles addressing the many ways in which extracellular matrix (ECM), or its components parts, can be used in regenerative medicine applications. ECM is a dynamic structure, composed of a three-dimensional architecture of fibrous proteins, proteoglycans, and glycosaminoglycans, synthesized by the resident cells. Consequently, ECM can be considered as nature’s ideal biologic scaffold material. The articles in this Special Issue cover a range of topics from the use of ECM components to manufacture scaffold materials, understanding how changes in ECM composition can lead to the development of disease, and how decellularization techniques can be used to develop tissue-derived ECM scaffolds for whole organ regeneration and wound repair. This editorial briefly summarizes the most interesting aspects of these articles.

【 授权许可】

Unknown