Introduction of ORF3a-Q57H SARS-CoV-2 Variant Causing Fourth Epidemic Wave of COVID-19, Hong Kong, China

Emerging Infectious Diseases

卷:27

关键词: respiratory infections;    severe acute respiratory syndrome coronavirus 2;    SARS-CoV-2;    SARS;    COVID-19;    coronavirus disease;   

DOI  :  10.3201/eid2705.210015

来源: DOAJ

【 摘 要 】

We describe an introduction of clade GH severe acute respiratory syndrome coronavirus 2 causing a fourth wave of coronavirus disease in Hong Kong. The virus has an ORF3a-Q57H mutation, causing truncation of ORF3b. This virus evades induction of cytokine, chemokine, and interferon-stimulated gene expression in primary human respiratory cells.

【 授权许可】

Unknown