Isotope Effects on Chemical Shifts in the Study of Hydrogen Bonds in Small Molecules

Molecules

卷:27

Poul Erik Hansen¹ 

[1] Department of Science and Environment, Roskilde University, Universitetsvej 1, DK-4000 Roskilde, Denmark;

关键词: hydrogen bonding;    isotope effects on ¹³C chemical shifts;    tautomerism;    hydrogen bond energy;    theoretical calculations;   

DOI  :  10.3390/molecules27082405

来源: DOAJ

【 摘 要 】

This review is giving a short introduction to the techniques used to investigate isotope effects on NMR chemical shifts. The review is discussing how isotope effects on chemical shifts can be used to elucidate the importance of either intra- or intermolecular hydrogen bonding in ionic liquids, of ammonium ions in a confined space, how isotope effects can help define dimers, trimers, etc., how isotope effects can lead to structural parameters such as distances and give information about ion pairing. Tautomerism is by advantage investigated by isotope effects on chemical shifts both in symmetric and asymmetric systems. The relationship between hydrogen bond energies and two-bond deuterium isotope effects on chemical shifts is described. Finally, theoretical calculations to obtain isotope effects on chemical shifts are looked into.

【 授权许可】

Unknown