Generation of two additional integration-free iPSC lines from related human donors

Stem Cell Research

卷:53

Daniel Faust¹  Anja Patricia Ramme²  Leopold Koenig³  Nhutuyen Nguyen³  Uwe Marx³ 

[1] TissUse GmbH, Oudenarder Str. 16, 13347 Berlin, Germany;

[2] Corresponding author.;

关键词: induced pluripotent stem cells;    iPSCs;    Stem cells;    Multi-Organ-Chips;    Organ-on-a-chip;    Differentiation;   

DOI  :  

来源: DOAJ

【 摘 要 】

The integration-free iPSC lines TISSUi006-A and TISSUi007-A were generated by reprogramming blood cells with episomal vectors. The male human donors belong to a Caucasian family in which four additional family members donated and iPSC lines were generated. All iPSC lines within this family are approved for commercial use by donor consent. Those iPSC lines offer the opportunity to study the influence of affiliation within one family. In future, more iPSCs lines of many more family members can be created to understand the effects of relatives with different ages on the reprogramming into iPSCs and differentiation into specific cell types.

【 授权许可】

Unknown