International Journal of Environmental Research and Public Health | 卷:12 |
Can Metabolic Disorders in Aging Men Contribute toProstatic Hyperplasia Eligible for Transurethral Resectionof the Prostate (TURP)? | |
Maria Laszczyńska1  Aleksandra Rył1  Marta Grabowska1  Marcin Słojewski2  Zuzanna Marcinowska3  Adriana Jędrzychowska3  Iwona Rotter4  | |
[1] Department of Histology and Developmental Biology, Pomeranian Medical University,Szczecin 71-210, Poland; | |
[2] Department of Urology and Urological Oncology, Pomeranian Medical University,Szczecin 71-111, Poland; | |
[3] Laboratory Diagnostics and Molecular Medicine, Department of Laboratory Medicine, Pomeranian Medical University, Szczecin 71-111, Poland; | |
[4] Laboratory of Rehabilitation Medicine, Pomeranian Medical University, Szczecin 71-210, Poland; | |
关键词: benign prostatic hyperplasia; metabolic syndrome; | |
DOI : 10.3390/ijerph120303327 | |
来源: DOAJ |
【 摘 要 】
Purpose: The aim of this study was to evaluate the incidence and severity of metabolic disorders occurring in the metabolic syndrome in patients with benign prostatic hyperplasia eligible for surgical treatment. Methods: The study group consisted men with diagnosed benign prostatic hyperplasia. The control group consisted patients recruited from basic health care units. Abdominal circumference, body weight and blood serum metabolic parameters were determined in the experimental and control groups. The concentrations of glucose were determined, as well as total cholesterol (ChT), low-density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides (TAG), by spectrophotometric method using reagent kits. Results: In the study group 91 (60.3%) cases of metabolic syndrome (MetS) were diagnosed, while in the control group 71 (46.1%) men met the diagnostic criteria for this syndrome (p = 0.018). The analysis shows a relationship between MetS in patients with BPH and concentration glucose, ChT, LDL, HDL,systolic blood pressure and diastolic blood pressure. We found no significant statistical relationship between body weight, abdominal circumference and concentration TAG, hypertension in patients and controls. Conclusions: in the study presented in this article, statistically significant relationships between BPH and the diagnostic parameters of the metabolic syndrome were demonstrated. These results indicate to the necessity of the modification of the lifestyle, taking preventive measures in diabetes, and evaluation of lipid metabolism disorders. It is recommended to assess symptoms that may suggest BPH (as a manifestation of LUTS) in men over 50 years of age with diagnoses of metabolic disorders (including MetS), and provide them with specialist urological care in order to prevent surgical treatment of the prostate.
【 授权许可】
Unknown