Hesitancy in COVID-19 vaccine uptake and its associated factors among the general adult population: a cross-sectional study in six Southeast Asian countries

Tropical Medicine and Health

Kittisak Jermsittiparsert¹  Aries Moralidad Baldonado²  Waqas Sami³  Roy Rillera Marzo⁴  Sharmila Mukund Borkar⁵  Swosti Acharya⁶  Sunil Shrestha⁷  Erwin Martinez Faller⁸  Md. Zakiul Alam⁹  Titik Respati^1,10  Karnjana Songwathana^1,11  Nhat Tan Pham^1,12  Mohammad Yasir Essar^1,13  Yadanar Aung^1,14  Siyan Yi^1,15 

[1] College of Innovative Business and Accountancy, Dhurakij Pundit University, Bangkok, Thailand;College of Nursing, Saint Alexius College, Koronadal, South Cotabato, Philippines;Department of Community Medicine and Public Health, College of Medicine, Majmaah University, 11952, Almajmaah, Saudi Arabia;Azra Naheed Medical College, Superior University, 54000, Lahore, Pakistan;Department of Community Medicine, International Medical School, Management and Science University, Shah Alam, Selangor, Malaysia;Department of Community Medicine, Faculty of Medicine, Asia Metropolitan University, Masai, Johor, Malaysia;Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Subang Jaya, Selangor, Malaysia;Department of Economics, Sridora Caculo College, Mapusa, Goa, India;Department of Nursing, Nepal Health Research and Innovation Foundation, Lalitpur, Province Bagmati, Nepal;Department of Pharmaceutical and Health Service Research, Nepal Health Research and Innovation Foundation, Lalitpur, Province Bagmati, Nepal;Department of Pharmacy, Faculty of Pharmacy, San Pedro College, Davao City, Philippines;Department of Population Sciences, University of Dhaka, Dhaka, Bangladesh;Department of Public Health, Faculty of Medicine and Faculty of Graduate Studies, Universitas Islam Bandung, Bandung, Indonesia;Faculty of Economics and Investment, Bangkok University, Bangkok, Thailand;International University, Ho Chi Minh City, Vietnam;Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam;Kabul University of Medical Sciences, Kabul, Afghanistan;Medical Statistics Division, Department of Medical Research, Pyin Oo Lwin, Myanmar;Institute for Population and Social Research, Mahidol University, Bangkok, Thailand;Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore;KHANA Center for Population Health Research, Phnom Penh, Cambodia;Center for Global Health Research, Touro University California, Vallejo, California, USA;

关键词: Immunization;    Pandemic;    Vaccine hesitancy;    Acceptance;    Multi-country study;    Southeast Asia;   

DOI  :  10.1186/s41182-021-00393-1

来源: Springer

【 摘 要 】

BackgroundVaccines are effective and reliable public health interventions against viral outbreaks and pandemics. However, hesitancy regarding the Coronavirus disease (COVID-19) vaccine is evident worldwide. Therefore, understanding vaccination-related behavior is critical in expanding the vaccine coverage to flatten the infection curve. This study explores the public perception regarding COVID-19 vaccination and identifies factors associated with vaccine hesitancy among the general adult populations in six Southeast Asian countries.MethodsUsing a snowball sampling approach, we conducted a descriptive cross-sectional study among 5260 participants in Indonesia, Malaysia, Myanmar, Philippines, Thailand, and Vietnam between February and May 2021. Binary logistic regression analysis with a backward conditional approach was applied to identify factors associated with COVID-19 vaccine hesitancy.ResultsOf the total, 50.6% were female, and the median age was 30 years (range: 15–83 years). The majority of the participants believed that vaccination effectively prevents and controls COVID-19 (81.2%), and 84.0% would accept COVID-19 vaccines when they become available. They agreed that health providers’ advice (83.0%), vaccination convenience (75.6%), and vaccine costs (62.8%) are essential for people to decide whether to accept COVID-19 vaccines. About half (49.3%) expressed their hesitancy to receive the COVID-19 vaccines. After adjustment for other covariates, COVID-19 vaccine hesitancy was significantly associated with age, residential area, education levels, employment status, and family economic status. Participants from Indonesia, Myanmar, Thailand, and Vietnam were significantly more likely to express hesitancy in receiving COVID-19 vaccines than those from Philippines.ConclusionsIn general, participants in this multi-country study showed their optimistic perception of COVID-19 vaccines’ effectiveness and willingness to receive them. However, about half of them still expressed their hesitancy in getting vaccinated. The hesitation was associated with several socioeconomic factors and varied by country. Therefore, COVID-19 vaccination programs should consider these factors essential for increasing vaccine uptake in the populations.

【 授权许可】

CC BY