Field application of nanoliposomes delivered quercetin by inhibiting specific hsp70 gene expression against plant virus disease

Journal of Nanobiotechnology

Kaiqiang Hao¹  Fenglong Wang²  Jinguang Yang²  Jie Wang²  Chenyu Su²  Lili Shen²  Fangfei Yu² 

[1] College of Plant Protection, Shenyang Agricultural University, 110866, Shenyang, China;Key Laboratory of Tobacco Pest Monitoring Controlling & Integrated Management, Tobacco Research Institute of Chinese Academy of Agricultural Sciences, 266101, Qingdao, China;

关键词: Plant virus disease;    Quercetin;    Nanoliposomes;    Field application;   

DOI  :  10.1186/s12951-021-01223-6

来源: Springer

【 摘 要 】

BackgroundThe annual economic loss caused by plant viruses exceeds 10 billion dollars due to the lack of ideal control measures. Quercetin is a flavonol compound that exerts a control effect on plant virus diseases, but its poor solubility and stability limit the control efficiency. Fortunately, the development of nanopesticides has led to new ideas.ResultsIn this study, 117 nm quercetin nanoliposomes with excellent stability were prepared from biomaterials, and few surfactants and stabilizers were added to optimize the formula. Nbhsp70er-1 and Nbhsp70c-A were found to be the target genes of quercetin, through abiotic and biotic stress, and the nanoliposomes improved the inhibitory effect at the gene and protein levels by 33.6 and 42%, respectively. Finally, the results of field experiment showed that the control efficiency was 38% higher than that of the conventional quercetin formulation and higher than those of other antiviral agents.ConclusionThis research innovatively reports the combination of biological antiviral agents and nanotechnology to control plant virus diseases, and it significantly improved the control efficiency and reduced the use of traditional chemical pesticides.Graphical Abstract

【 授权许可】

CC BY