Epilepsy and other seizure disorders in acute psychiatric inpatients

BMC Psychiatry

Sverre Georg Sæther¹  Eylert Brodtkorb²  Erlend Iversen Nakken³  Frithjof Grinde³  Arne Vaaler⁴  Ole Kristian Drange⁵ 

[1]Blue Cross Lade Addiction Treatment Center, Trondheim, Norway

[2]Department of Neurology and Clinical Neurophysiology, St. Olavs University Hospital, Trondheim, Norway

[3]Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway

[4]Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway

[5]Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway

[6]Department of Acute Psychiatry, Division of Mental Healthcare, St. Olavs University Hospital, Trondheim, Norway

[7]Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway

[8]Department of Acute Psychiatry, Division of Mental Healthcare, St. Olavs University Hospital, Trondheim, Norway

[9]Department of Psychiatry, Sørlandet Hospital HF, Kristiansand, Norway

关键词: Epilepsy;    Seizures;    Acute psychiatric disorders;    Acute psychiatry;    Prevalence;   

DOI  :  10.1186/s12888-021-03619-y

来源: Springer

【 摘 要 】

BackgroundIt is well known that patients with epilepsy have a high rate of psychiatric comorbidity. However, studies exploring epilepsy in psychiatric cohorts are scarce. The aim of this study was to examine the prevalence of seizure disorders in acute psychiatric inpatients.MethodsThis is a cross-sectional study performed in a catchment-area based acute psychiatric department. All patients (age > 18) admitted during September 2011 - March 2012 were eligible for inclusion. Consenting patients were screened for a life-time history of epilepsy or seizures using self-reported questionnaire data and diagnostic codes for epilepsy in hospital and National registries. Patients scoring positive to one or more of these screening criteria underwent a thorough diagnostic validation (chart review), and the seizure disorders were classified as epilepsy, acute symptomatic seizures and/or psychogenic non-epileptic seizures according to current definitions.ResultsA total of 380 out of 591 (64.3%) consecutively admitted patients consented to participate in the study. Eighty-nine patients (23.4%) scored positive to one or more screening criteria. Fifteen (3.9%) were classified with epilepsy, 21 (5.5%) with acute symptomatic seizures and 9 (2.4%) with psychogenic non-epileptic seizures.ConclusionsThis is the first study to report on the prevalence of seizure disorders in acute psychiatric inpatients. The life-time prevalence of epilepsy in this cohort of patients is five – six times as high as reports in the general population. These findings underscore the need for the clinical psychiatrist to have comprehensive knowledge on the interface between epileptology and psychiatry.Trials registrationClinicalTrials.gov identifier NCT01415323.

【 授权许可】

CC BY