The physiological and psychological effects of cognitive behavior therapy on patients with inflammatory bowel disease before COVID-19: a systematic review

BMC Gastroenterology

Ying Xie¹  Yuhao Sun¹  Ran Li¹  Jie Chen²  Therese Hesketh³  Xuejie Chen⁴  Xiaoyan Wang⁴ 

[1] Centre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, 310058, Hangzhou, People’s Republic of China;Centre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, 310058, Hangzhou, People’s Republic of China;Department of Gastroenterology, Central South University, The Third Xiangya Hospital138 Tongzipo Road, 410013, Changsha, Hunan, People’s Republic of China;Centre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, 310058, Hangzhou, People’s Republic of China;Institute for Global Health, University College London, 30 Guilford St, WC1N1EH, London, UK;Department of Gastroenterology, Central South University, The Third Xiangya Hospital138 Tongzipo Road, 410013, Changsha, Hunan, People’s Republic of China;

关键词: Cognitive behavior therapy;    Inflammatory bowel disease;    Quality of life;    Depression;    Crohn's disease;    Ulcerative colitis;   

DOI  :  10.1186/s12876-021-02003-0

来源: Springer

【 摘 要 】

ObjectiveCognitive behavioral therapy (CBT) is now included in the treatment of patients with inflammatory bowel disease (IBD) in many settings. However, different clinical trials report different outcomes without consensus. This study aims to evaluate the impact of CBT on the mental state, quality of life and disease activity of patients with IBD.DesignSystematic review.MethodsThis systematic review searched eligible studies from 1946 to December 8, 2019, in MEDLINE, EMBASE, CINAHL, Cochrane library, ClinicalTrials.gov, PsycINFO, Web of Science for eligible randomized controlled trials (RCT).ResultsAmong the initial identified 1807 references, 11 studies met inclusion criteria. CBT was shown to improve patient's quality of life and reduce the level of depression and anxiety post-intervention but was not sustained. Evidence is not enough for the effect of CBT on disease activity, or C-reactive protein level.ConclusionsCBT has shown short-term positive psychological effects on IBD patients, but there is insufficient evidence for sustained physical and psychological improvements of IBD patients.PROSPERO registration: CRD42019152330.

【 授权许可】

CC BY