Mortality by opioid poisoning in children and teenagers and opioid prescriptions

BMC Pediatrics

Elise Cranfield¹  Patrice Forget²  Elizabeth Ashcroft³ 

[1] Edinburgh Medical School, College of Medicine and Veterinary Medicine, EH16 4TJ, Edinburgh, UK;Institute of Applied Health Sciences, Epidemiology group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen; Department of Anaesthesia, NHS Grampian, AB25 2ZD, Aberdeen, UK;University of Aberdeen, AB25 2ZD, Aberdeen, UK;

关键词: Opioid;    Poisoning;    Children;    Teenagers;    Prescriptions;   

DOI  :  10.1186/s12887-021-03061-9

来源: Springer

【 摘 要 】

BackgroundNo comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England.AimTo investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England.MethodsA retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning.ResultsThe number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05).ConclusionDespite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning.

【 授权许可】

CC BY