Ligation-assisted endoscopic mucosal resection has high complete resection rate in rectal carcinoid tumor

BMC Gastroenterology

Cheng-Tang Chiu¹  Ming-Yao Su² 

[1] Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taoyuan, Taiwan;Chang Gung University College of Medicine, Taoyuan, Taiwan;Taiwan Association for the Study of Small Intestinal Diseases, Taoyuan, Taiwan;Department of Internal Medicine, New Taipei Municipal TuCheng Hospital, 6, Sec 2, Jincheng Rd, Tucheng Dist, New Taipei City, Taiwan, Republic of China;Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taoyuan, Taiwan;Chang Gung University College of Medicine, Taoyuan, Taiwan;Taiwan Association for the Study of Small Intestinal Diseases, Taoyuan, Taiwan;

关键词: Carcinoid;    Neuroendocrine tumor;    Endoscopic mucosal resection;    Ligation;   

DOI  :  10.1186/s12876-021-02061-4

来源: Springer

【 摘 要 】

AimWe aimed to compare the outcomes of different therapeutic modalities in rectal carcinoid tumors.MethodWe retrospectively collected 145 patients with rectal carcinoid tumors which were pathologically diagnosed from 2005/01/01 to 2016/12/31. We compared tumor size, complete resection rate and recurrent rate between different therapeutic modalities. Then, prospectively compared the treatment outcomes of 28 patients treated with ligation assisted endoscopic mucosal resection (LEMR) and 25 patients treated with endoscopic mucosal resection with cap (EMRC).ResultThe mean size of tumors was 6.5 mm (1–25 mm), and the mean follow-up duration was 26 months (6–118 months). The therapeutic modalities included ligation-assisted endoscopic mucosal resection (LEMR) (25 tumors, 17%), endoscopic mucosal resection (EMR) (31 tumors, 21%), snare polypectomy (30 tumors, 21%), biopsy forceps removal (46 tumors, 32%) and surgical resection (13 tumors, 11%), including 6 tumors treated with transanal endoscopic microsurgery (TEM) method. In view of pathologically complete resection rate, LEMR was highest (100%), followed by surgical resection (85%). However, EMR only had 42% pathologically complete resection rate. Besides, LEMR and surgical resection had no local recurrence and significantly higher clinically complete resection rate, compared to other treatments. For the further prospective study, complete resection was noted in 28 (100%) patients in LEMR group and 13 (52%) patients in EMRC group.ConclusionIn the treatment of rectal carcinoid tumors, LEMR is safe and effective compared with traditional endoscopic treatments.

【 授权许可】

CC BY