Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report

Surgical Case Reports

Takao Ohtsuka¹  Akihiro Nakajo¹  Yoichi Yamasaki¹  Tetsuya Idichi¹  Kiyonori Tanoue¹  Yoshiaki Kita¹  Hiroshi Kurahara¹  Yota Kawasaki¹  Yuko Mataki¹  Yuto Hozaka¹  Satoshi Iino²  Masahiko Sakoda³  Takaaki Arigami⁴ 

[1] Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, 890-8520, Kagoshima, Japan;Department of Digestive Surgery, Kagoshima City Hospital, Kagoshima, Japan;Department of Digestive Surgery, Kagoshima Kouseiren Hospital, Kagoshima, Japan;Department of Onco-biological Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;

关键词: Hepatocellular carcinoma;    Recurrence;    Extrahepatic metastasis;    Cervical lymph node metastasis;   

DOI  :  10.1186/s40792-021-01352-y

来源: Springer

【 摘 要 】

BackgroundHepatocellular carcinoma (HCC) patients with metastases to the cervical lymph nodes are extremely rare, and its clinical course is characterized by rapidly progressive disease. Hence, there have been no reports of metastatic cervical lymph node recurrence indicated after a long postoperative surveillance period.Case presentationThe patient was a 63-year-old male who underwent right hepatectomy for HCC of the right upper lobe. Three years after resection, metastatic lymph node recurrence was detected in the subdiaphragm, superior mediastinum, and right cervical lymph nodes. The patient underwent excisional biopsy of the cervical lymph node, followed by molecular-targeted therapy and radiation therapy. Lenvatinib reduced the size of all metastatic lymph nodes and the patient survived for a relatively long period of 43 months after the recurrence was detected.ConclusionsAfter resection of HCC in the right upper lobe, there is the possibility of metastatic lymph node recurrence in unusual sites, including the cervical region, and lenvatinib may be effective in those recurrences.

【 授权许可】

CC BY