Study on the correlation between preoperative inflammatory indexes and adhesional perinephric fat before laparoscopic partial nephrectomy

BMC Urology

Lin Cong¹  Xiaojiao Li²  Qianqian Hua²  Ximing Wang²  Teng Ma²  Zhaoqin Huang²  Yunchao Chen²  Qianli Ma³ 

[1] Department of Medical Imaging Interventional Therapy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250021, Jinan, Shandong, China;Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jingwu Road, 250021, Jinan, Shandong, China;Department of Radiology, Taian City Central Hospital, 271000, Taian, Shandong, China;

关键词: Preoperative composite inflammatory index;    Adhesional perinephric fat;    Laparoscopic partial nephrectomy;    Renal cell carcinoma;   

DOI  :  10.1186/s12894-021-00940-2

来源: Springer

【 摘 要 】

ObjectiveThis study was aimed to evaluate the effect of preoperative composite inflammatory index on adhesional perinephric fat (APF), providing a help for preoperative risk assessment of laparoscopic partial nephrectomy (LPN) in patients with renal cell carcinoma.Materials and methodsA retrospective study was conducted on 231 patients with renal cell carcinoma, who underwent laparoscopic partial nephrectomy. They were divided into two groups according to whether there was APF during operation. Relevant clinical data, laboratory parameters and imaging examination were obtained before operation to calculate the composite inflammatory index and MAP score. The composite inflammatory index was divided into high value group and low value group by ROC curve method. The related predictive factors of APF were analyzed by logistic regression method.ResultsThe APF was found in 105 patients (45.5%). In multivariate analysis, systemic immune inflammation index (SII) (high/low), MAP score, tumor size and perirenal fat thickness were independent predictors of APF. The operation time of patients with APF was longer, and the difference of blood loss was not statistically significant.ConclusionSII is an independent predictor of APF before laparoscopic partial nephrectomy.Trial registration ChiCTR, ChiCTR2100045944. Registered 30 April 2021—Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=125703.

【 授权许可】

CC BY