Osteonecrosis of the humeral head in a human immunodeficiency virus-infected patient under tenofovir disoproxil fumarate–emtricitabine–lopinavir/ritonavir for 10 years: a case report

Journal of Medical Case Reports

Bruce Shinga Wembulua¹  Kalilou Diallo²  Noel Magloire Manga²  Armel Alleyo³  Mohamadou Aidara⁴ 

[1] Department of Infectious and Tropical Diseases, Fann University Hospital, Dakar, Senegal;Unit of Infectious and Tropical Diseases, Assane Seck University, Hospital de la Paix, Ziguinchor, Senegal;Unit of Orthopedics and Traumatology, Hospital de la Paix, Ziguinchor, Senegal;Unit of Radiology, Hospital de la Paix, Ziguinchor, Senegal;

关键词: Aseptic osteonecrosis;    Humeral head;    HIV-infected patients;    Antiretroviral therapy;    Case report;   

DOI  :  10.1186/s13256-021-03145-1

来源: Springer

【 摘 要 】

BackgroundHuman immunodeficiency virus-infected patients are 100 times more likely to develop aseptic osteonecrosis compared with the general population. While 90% of cases concern the femoral head, the involvement of humeral bone remains rare.Case presentationWe report a case of aseptic osteonecrosis of the left humeral head complicating antiretroviral therapy in a female, 46-year-old, Bissau-Guinean human immunodeficiency virus-infected patient received in a context of progressive pain in the left shoulder followed by limitation of articular movements. Standard x-ray of the shoulder allowed us to make the diagnosis by showing a typical image of osteonecrosis. The treatment was medical combined with physiotherapy.ConclusionsAseptic osteonecrosis should be systematically looked for in human immunodeficiency virus patients on antiretroviral treatment. In addition to femoral head aseptic necrosis, the involvement of the humeral bone should also be considered.

【 授权许可】

CC BY