BMC Pregnancy and Childbirth | |
Association between halitosis and female fecundability in China: a prospective cohort study | |
Yulin Yang1  Hao Zhang2  Rong Huang3  Jiangfeng Ye3  Jun Zhang4  Lin Zhang5  Xiaona Huo6  | |
[1] Department of Maternal and Child Health Care, Shanghai Municipal Health and Family Planning Commission, 300 Expo Village Road, 200125, Shanghai, China;Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, 356 East Beijing Road, 200001, Shanghai, China;MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, 200092, Shanghai, China;MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, 200092, Shanghai, China;Hainan Women and Children’s Medical Center, Haiko, Hainan, China;Obstetrics Department, International Peace Maternity and Child Health Hospital of China, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, China;Obstetrics and Gynecology Department, International Peace Maternity and Child Health Hospital of China, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, China;MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, 200092, Shanghai, China; | |
关键词: Halitosis; Oral hygiene; Oral health; Fecundability; Time to pregnancy; | |
DOI : 10.1186/s12884-021-04315-1 | |
来源: Springer | |
【 摘 要 】
BackgroundPeriodontal diseases and poor oral hygiene are potentially associated with decreased female fecundability. Fecundability refers to the probability of conception during a given period measured in months or menstrual cycles. This study aims to examine whether halitosis is associated with female fecundability in a large sample of Chinese women who planned to be pregnant.MethodsIn 2012, a total of 6319 couples came for preconception care in eight districts in Shanghai, China and were followed by telephone contact. Three thousand nine hundred fifteen women who continued trying to be pregnant for up to 24 months remained for final statistical analyses. Halitosis was self-reported at the preconception care visit. Time to pregnancy (TTP) was reported in months and was censored at 24 months. Fecundability ratio (FR) was defined as the ratio of probability of conception among those with and without halitosis. FR and 95% confidence interval (CI) were estimated using the discrete-time Cox model.Results80.1 and 86.1% of women had self-reported clinically confirmed pregnancy within 12 and 24 months, respectively. Halitosis was reported in 8.7% of the women. After controlling for potential confounders, halitosis was associated with a reduced probability of spontaneous conception (for an observation period of 12 months: adjusted FR 0.82, 95% CI 0.72–0.94; for an observation period of 24 months: adjusted FR 0.84, 95% CI 0.74–0.96).ConclusionsHalitosis is associated with reduced fecundability in Chinese women.
【 授权许可】
CC BY
【 预 览 】
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