Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report

BMC Infectious Diseases

Jianling Huang¹  Wenjing Wang¹  Bo Han¹  Lixu Xie¹  Ganzhu Feng¹  Changwen Zhang¹  Tianming Gao¹  Changjun Zhu¹  Minjie Lv¹ 

[1] Department of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical University, 210000, Nanjing, China;

关键词: Bloodstream infection;    Pneumonia;    Chlamydia abortus;    Case report;   

DOI  :  10.1186/s12879-022-07158-z

来源: Springer

【 摘 要 】

BackgroundChlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia.Case presentationWe present details of a patient with bloodstream infection and pneumonia caused by Chlamydia abortus. Both blood next-generation sequencing (NGS) and sputum NGS indicate Chlamydia abortus infection. The patient received intravenous infusion of piperacillin sodium and tazobactam sodium (4.5 g/8 h) and moxifloxacin (0.4 g/d) and oral oseltamivir (75 mg/day). Within one month of follow-up, the patient's clinical symptoms were significantly improved, and all laboratory parameters showed no marked abnormality. However, chest computer tomography (CT) showed the inflammation wasn’t completely absorbed. And we are still following up.ConclusionsChlamydia abortus can cause pneumonia in humans. NGS has the particular advantage of quickly and accurately identifying the infection of such rare pathogens. Pneumonia is generally not life-threatening, and has a good prognosis with appropriate treatment. However, Chlamydia infection can lead to serious visceral complications which clinicians should pay attention to.

【 授权许可】

CC BY