Use of the painDETECT to discriminate musculoskeletal pain phenotypes

Archives of Physiotherapy

Felipe José Jandre Reis¹  Márcia Cliton Bezerra²  Juliana Valentim Bittencourt²  Arthur de Sá Ferreira²  Mônica Rotondo Pina²  Leandro Alberto Calazans Nogueira³ 

[1]Physiotherapy Department at Federal Institute of Rio de Janeiro (IFRJ), Rio de Janeiro, Brazil

[2]Rehabilitation Science Postgraduate Program at Augusto Motta University Centre (UNISUAM), Paris, 84, Bonsucesso, CEP 21041-020, Rio de Janeiro, RJ, Brazil

[3]Rehabilitation Science Postgraduate Program at Augusto Motta University Centre (UNISUAM), Paris, 84, Bonsucesso, CEP 21041-020, Rio de Janeiro, RJ, Brazil

[4]Physiotherapy Department at Federal Institute of Rio de Janeiro (IFRJ), Rio de Janeiro, Brazil

关键词: Musculoskeletal pain;    Neuropathic pain;    Pain mechanisms;    Central nervous system sensitization;    Diffuse noxious inhibitory control;   

DOI  :  10.1186/s40945-022-00129-2

来源: Springer

【 摘 要 】

BackgroundMusculoskeletal pain patients present similar pain characteristics regardless of the clinical diagnosis. PainDETECT questionnaire is useful for screening neuropathic-like symptoms in many musculoskeletal conditions. However, no previous studies compared pain phenotypes of patients with musculoskeletal pain using the painDETECT. Therefore, the current study aimed to compare the pain characteristics of patients with musculoskeletal pain classified according to the painDETECT as nociceptive pain, unclear, and neuropathic-like symptoms.MethodsA cross-sectional study was conducted in 308 participants with musculoskeletal pain. Demographic and clinical characteristics of the participants were examined. Neuropathic-like symptoms, pain intensity, pain area, Central Sensitization-related sign and symptoms, functional limitation, and conditioned pain modulation were assessed in patients with musculoskeletal pain. Independent one-way analysis of variance (ANOVA) was used to test for between-group differences for the outcome measures with continuous variables and Pearson chi-square test verified between-group differences on the efficiency of the conditioned pain modulation.ResultsParticipants had a mean age of 52.21 (±15.01) years old and 220 (71.42%) were females. One hundred seventy-three (56.16%) participants present nociceptive pain, 69 (22.40%) unclear, and 66 (21.42%) neuropathic-like symptoms. A one-way ANOVA showed differences for the pain intensity [F (2,305) = 20.097; p < .001], pain area [F (2,305) = 28.525; p < .001], Central Sensitization-related sign and symptoms [F (2,305) = 54.186; p < .001], and functional limitation [F (2,256) = 8.061; p < .001]. However, conditioned pain modulation was similarly impaired among the three groups (X2 = 0.333, p = 0.847).ConclusionPatients with neuropathic-like symptoms revealed unfavorable pain characteristics compared to their counterparts, including pain intensity, generalized pain, Central Sensitization-related sign and symptoms, and functional limitation.

【 授权许可】

CC BY