Prevalence of chronic cough in China: a systematic review and meta-analysis

BMC Pulmonary Medicine

Fang Yi¹  Jingyi Liang¹  Mei Jiang¹  Weiyan Ye¹  Zhufeng Wang¹  Kefang Lai¹  Hanwen Liang² 

[1] National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China;National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China;Guangzhou Blood Center, Guangzhou, Guangdong, China;

关键词: China;    Cough;    Chronic diseases;    Meta-analysis;    Prevalence;   

DOI  :  10.1186/s12890-022-01847-w

来源: Springer

【 摘 要 】

BackgroundIndividual studies have indicated variable prevalence for chronic cough, but thus far, there has been no systematic report on the prevalence of this condition.MethodsIn this study, we performed a systematic review and meta-analysis by searching databases including PubMed, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese biomedical literature service system, Wanfang Database, and VIP database, for studies on chronic cough in China published before December 28, 2020. A random effects model was used to calculate pooled prevalence estimates with 95% confidence interval [95%CI], weighted by study size.ResultsFifteen studies with 141,114 community-based adults were included in the study, showing a prevalence of 6.22% (95% CI 5.03–7.41%). And 21 studies with 164,280 community-based children were included, presenting a prevalence of 7.67% (95% CI 6.24–9.11%). In subgroup meta-analyses, the prevalence in adults was 4.38% (95% CI 2.74–6.02%) in southern China and 8.70% (95% CI 6.52–10.88%) in northern China. In the children population, the prevalence in northern China was also higher than in southern China (northern vs. southern: 7.45% with a 95% CI of 5.50–9.41%, vs. 7.86% with a 95% CI of 5.56–10.16%).ConclusionsOur population-based study provides relatively reliable data on the prevalence of chronic cough in China and may help the development of global strategies for chronic cough management.

【 授权许可】

CC BY