Exploring protective and risk factors in the home environment in high-risk families – results from the Danish High Risk and Resilience Study—VIA 7

BMC Psychiatry

Katrine Spang¹  Camilla Jerlang Christiani¹  Ditte Ellersgaard²  Birgitte Klee Burton³  Nicoline Hemager⁴  Jens Richardt Møllegaard Jepsen⁵  Anne Amalie Elgaard Thorup⁶  Kerstin J. Plessen⁷  Merete Nordentoft⁸  Henriette Stadsgaard⁹  Maria Toft Henriksen⁹  Aja Neergaard Greve⁹  Vibeke Bliksted⁹  Kate Kold Zahle⁹  Ditte Lou Gantriis⁹  Ole Mors⁹ 

[1] The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;CORE Copenhagen Research Unit, Mental Health Centre Copenhagen, Copenhagen University Hospital, Mental Health Services Capital Region, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark;CORE Copenhagen Research Unit, Mental Health Centre Copenhagen, Copenhagen University Hospital, Mental Health Services Capital Region, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark;Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Copenhagen, Denmark;CORE Copenhagen Research Unit, Mental Health Centre Copenhagen, Copenhagen University Hospital, Mental Health Services Capital Region, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark;Division of Child and Adolescent Psychiatry, Department of Psychiatry, University Medical Center, University of Lausanne, Lausanne, Switzerland;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;CORE Copenhagen Research Unit, Mental Health Centre Copenhagen, Copenhagen University Hospital, Mental Health Services Capital Region, Copenhagen, Denmark;The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark;Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark;

关键词: Home environment;    Risk factors;    Schizophrenia;    Bipolar disorder;    Familial high-risk;   

DOI  :  10.1186/s12888-022-03733-5

来源: Springer

【 摘 要 】

BackgroundExposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder.MethodsFrom a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment.ResultsWhen analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately.ConclusionsKnowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.

【 授权许可】

CC BY