Depressive and anxiety symptoms among Japanese cancer survivors: Japan cancer survivorship research project

BMC Cancer

Mitsue Saito¹  Gautam A. Deshpande²  Go Muto³  Kiyomi Mitsui⁴  Yasuhisa Terao⁵  Satoru Takeda⁵  Yan Yan⁶  Katsuji Nishimura⁷  Rie Akaho⁷  Kentaro Matsui⁸  Takeshi Tanigawa⁹  Yuito Ueda⁹  Motoki Endo⁹  Yuya Imai⁹  Kazuhiko Hayashi^1,10 

[1] Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan;Department of General Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan;Department of Hygiene, Kitasato University School of Medicine, Kanagawa, Japan;Department of Hygiene, Public Health, and Preventive Medicine, Showa University, Tokyo, Japan;Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, Tokyo, Japan;Department of Palliative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan;Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan;Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan;Department of Clinical Laboratory and Department of Sleep-Wake Disorders, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan;Department of Public Health, Juntendo University Faculty of Medicine, Tokyo, Japan;St. Marianna University School of Medicine, Kawasaki, Japan;

关键词: Depressive symptoms;    Anxiety;    Cancer survivors;    HADS;   

DOI  :  10.1186/s12885-022-09215-x

来源: Springer

【 摘 要 】

BackgroundThis study aimed to clarify predictors of depressive symptoms and anxiety symptoms after cancer diagnosis among Japanese cancer survivors (CSs).MethodsAs part of a Japanese cancer survivorship research project commissioned by the Ministry of Health, Labour and Welfare (MHLW) of Japan, we conducted a web-based nationwide survey of CSs in 2018. We analyzed the risk factors for depressive and anxiety symptoms, as measured by the Hospital Anxiety and Depression Scale Japanese version (HADS).ResultsOf 1,234 Japanese CSs, mean score of HADS-depression and HADS-anxiety were 4.08 and 4.78, respectively. At the time of the study, the number of CSs with symptoms of depression and anxiety were 111 (9.0%) and 269 (21.8%), respectively. After multivariable analysis, CSs ≥ 60 years old (reference: ≤ 39 years old, odds ratios (OR): 0.39, 95%CI: 0.17–0.90) and those ≥ 10 years from cancer diagnosis (reference: 0–4 years, OR: 0.55, 95%CI: 0.32–0.96) had lower odds for depressive symptoms. And CSs ≥ 60 years old (reference: ≤ 39 years old, OR: 0.27, 95%CI: 0.15–0.49) and those ≥ 10 years from cancer diagnosis (reference: 0–4 years, OR: 0.62, 95%CI: 0.42–0.90) also had lower odds for anxiety symptoms. CSs who received chemotherapy (OR: 1.56, 95%CI: 1.10–2.20) had higher odds for anxiety symptoms.ConclusionsBased on manifestation of symptoms, CSs who were younger, closer to the time of cancer diagnosis, had advanced-staged cancer, or received chemotherapy may be at higher risk for depressive or anxiety symptoms. Those CSs who have higher risk for depression and anxiety symptoms, should be followed-up more carefully for better cancer survivorship, by medical professionals, companies, and society.

【 授权许可】

CC BY