Development of a patient reported outcome instrument for chronic sialadenitis

Journal of Otolaryngology - Head & Neck Surgery

Fatemeh Ramazani¹  Daniel O’Connell¹  Amr Hamour¹  David W. J. Côté¹  Caroline C. Jeffery¹  Yaser Alrajhi¹  Vincent Biron¹ 

[1] Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, 1E4 Walter C. MacKenzie Health Sciences Centre, University of Alberta, T6G 2B7, Edmonton, AB, Canada;

关键词: Sialendoscopy;    Sialadenitis;    Patient reported outcomes;   

DOI  :  10.1186/s40463-022-00555-z

来源: Springer

【 摘 要 】

BackgroundSialendoscopy assisted treatments are a minimally invasive management modality for chronic sialadenitis. Clinicians report improved patient quality of life (QoL) following sialendoscopy assisted treatments, but there exist gaps in current literature about patient reported outcomes (PROs). PROs are outcome measures developed based on patient perceptions.ObjectiveThe objective of this study was to create a PRO instrument for chronic sialadenitis, to assess the efficacy of sialendoscopy assisted treatments in improve patients’ QoL.DesignThis four-phase qualitative study employed grounded theory methodology and a modified Delphi technique. In Phase I, ten patients were interviewed to identify the QoL domains impacted by chronic sialadenitis. In Phase II, these QoL domains were presented to a focus group of different chronic sialadenitis patients, who were asked to rank them by order of importance. A conceptual framework of QoL domains impacted by chronic sialadenitis was created based on patient consensus. Itemization of the PRO questionnaire was done by a focus group of four Otolaryngologists in phase III. Lastly, the questionnaire was completed in Phase IV by cognitive interviewing of five new chronic sialadenitis patients; ensuring ease of understanding and clarity.ResultsPatients identified 15 domains of QoL impacted by chronic sialadenitis, divided into three sub-scales: physical symptoms, psychosocial symptoms, and activity restriction. These domains provided the basis for creation of a 22-item PRO questionnaire, with a Likert-type response scale.ConclusionClinical application of the novel questionnaire produced by this study will allow for a patient-centered assessment of the patient reported effectiveness of sialendoscopy assisted therapies for management of chronic sialadenitis.Level of evidence Level V.Graphical Abstract

【 授权许可】

CC BY