Glutathione peroxidase‐1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice

Aging Cell

Rahul Kumar¹  Sanjana Dayal¹  Hao Feng²  Yi Chu²  Dao‐Fu Dai²  Rui Huang³  Kung‐Sik Chan³  Renny S. Lan⁴ 

[1]Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa

[2]Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa

[3]Department of Statistics and Actuarial Science, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa

[4]Proteomics Core, Department of Biochemistry and Molecular Biology, University of Arkansas Medical Sciences College of Medicine, Little Rock, Arkansas

关键词: glutathione peroxidase‐1;    kidney aging;    mitochondria;    proteomics;    reactive oxygen species;   

DOI  :  10.1111/acel.13154

来源: Wiley

【 授权许可】

CC BY