Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti‐inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway

Journal of Cellular and Molecular Medicine

Jun Liu¹  Jun Zhou²  Qingfu Wang²  Anmin Ruan³  Lingfeng Zeng⁴  Pu Chen⁵ 

[1] Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China;Guangdong Second Traditional Chinese Medicine Hospital (Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou, China;Department of Orthopaedic Surgery, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China;Department of Orthopaedic Surgery, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China;Department of Orthopaedic Surgery, Beijing Longfu Hospital, Beijing, China;Department of Orthopaedic Surgery, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine (The 2nd Affiliated Hospital), Guangzhou, China;Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China;Department of Orthopaedic Surgery, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine (The 2nd Affiliated Hospital), Guangzhou, China;Department of Orthopaedic Surgery, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China;

关键词: bioinformatics analysis;    cinnamic aldehyde;    experimental pharmacology;    network pharmacology;    osteoarthritis;    synovial inflammation;    TLR4/MyD88 signalling pathway;   

DOI  :  10.1111/jcmm.17148

来源: Wiley

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