Smad7 deficiency decreases iron and haemoglobin through hepcidin up‐regulation by multilayer compensatory mechanisms

Journal of Cellular and Molecular Medicine

Junxia Min¹  Xuyan He¹  Qian Wu¹  Xinhui Wang¹  Zhidan Xia¹  Jiaming Wang¹  Peng An¹  Hao Wang²  Fudi Wang²  Yan Chen³ 

[1] Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China;School of Public Health, The First Affiliated Hospital, Institute of Translational Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Medicine, Zhejiang University, Hangzhou, China;Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China;School of Public Health, The First Affiliated Hospital, Institute of Translational Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Medicine, Zhejiang University, Hangzhou, China;Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China;Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China;

关键词: Bambi;    follistatin;    hepcidin;    iron deficiency;    Smad6;    Smad7;   

DOI  :  10.1111/jcmm.13546

来源: Wiley

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