RNA methyltransferase METTL3 induces intrinsic resistance to gefitinib by combining with MET to regulate PI3K/AKT pathway in lung adenocarcinoma

Journal of Cellular and Molecular Medicine

Chang Zhang¹  Tianyu Qu²  Renhua Guo²  Fangyan Gao²  Jingya Zhang²  Chen Zhang²  Qianqian Wang²  Jifu Wei³ 

[1] Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China;Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, China;Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;Research Division of Clinical Pharmacology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;

关键词: gefitinib resistance;    lung adenocarcinoma;    METTL3;    RNA methyltransferase;   

DOI  :  10.1111/jcmm.16114

来源: Wiley

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