期刊论文详细信息
Molecular Systems Biology | |
Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens | |
Andrew R Leach1  Aldo Segura‐Cabrera1  Claire Crafter2  Ben Sidders2  James T Lynch2  Stephen Fawell3  James Morris4  Ermira Lleshi4  Fiona M Behan4  Clare Pacini4  Howard Lightfoot4  Frances Thomas4  James Hall4  Patricia Jaaks4  Donny van der Meer4  Iman Mali4  Gabriele Picco4  Alexandra Beck4  Laura Richardson4  Elizabeth A Coker4  Charlotte Tolley4  Andrew Barthorpe4  Tatiana Mironenko4  Wanjuan Yang4  Mathew J Garnett4  Caitlin Hall4  Emanuel Gonçalves4  Francesco Iorio5  | |
[1] European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK;Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK;Research and Early Development, Oncology R&D, AstraZeneca, Waltham, MA, USA;Wellcome Sanger Institute, Hinxton, UK;Wellcome Sanger Institute, Hinxton, UK;Human Technopole, Milano, Italy; | |
关键词: CRISPR; drug mechanism‐of‐action; protein networks; | |
DOI : 10.15252/msb.20199405 | |
来源: Wiley | |