MET inhibition enhances PARP inhibitor efficacy in castration‐resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways

Journal of Cellular and Molecular Medicine

Qi Wang¹  Zhenwei Wang²  Sihai Zhou³  Liqin Yang³  Zhiyu Liu³  Xiang Gao³  Zhihong Dai³  Liang Wang³ 

[1] Department of Respiratory Medicine, The Second Affiliated Hospital of Dalian Medical University, DaLian, China;Department of Urology, Guangdong Second Provincial General Hospital, Guangzhou, China;Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China;

关键词: ATM/ATR pathway;    CRPC;    DNA damage response;    MET inhibitor;    PARP inhibitor;    PI3K/AKT pathway;   

DOI  :  10.1111/jcmm.17037

来源: Wiley

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