Berberine ameliorates aGVHD by gut microbiota remodelling, TLR4 signalling suppression and colonic barrier repairment for NLRP3 inflammasome inhibition

Journal of Cellular and Molecular Medicine

Lipei Wang¹  Chengping Wen¹  Tianyi Li¹  Shuijuan Zhang¹  Yanna Zhao²  Jiefeng Huang³ 

[1] College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China;College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China;Institute of Hematology Research, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China;Institute of Hematology Research, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China;

关键词: acute graft‐versus‐host disease;    berberine;    cytokines;    gut microbiota;    NLRP3 inflammasome;    TLR4 signaling pathway;   

DOI  :  10.1111/jcmm.17158

来源: Wiley

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