Mutational landscape and genetic signatures of cell‐free DNA in tumour‐induced osteomalacia

Journal of Cellular and Molecular Medicine

Yu Zheng¹  Zhihong Wu²  Yalun Li³  Yuchen Niu⁴  Huizi Wang⁴  Xin‐Zhuang Yang⁴  Weibo Xia⁵  Mei Li⁵  Na Gao⁶  Yong Liu⁶  Yuan Xu⁶  Ying Liu⁶  Ying Yang⁶  Xi Zhou⁶  Na Zhang⁶  Wenli Li⁶  Jia Liu⁶  Xu Yang⁶  Zhen Zhang⁷  Jiaqi Liu⁸  Weisheng Chen⁹  Nan Wu^1,10  Sen Liu^1,10  Jianguo Zhang^1,10  Guixing Qiu^1,10  Hengqiang Zhao^1,11  Yingli Sun^1,12  Yong Wu^1,13  Yang Shao^1,13  Xian Zhang^1,13  Yue Ming^1,14  Jianzhong Su^1,15  Meng Zhou^1,15  Hua Bao^1,16  Xue Wu^1,16 

[1] Beijing Ekitech Co. Ltd., Beijing, China;Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China;Key laboratory of big data for spinal deformities, Chinese Academy of Medical Sciences, Beijing, China;Department of Central Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Department of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China;Department of Central Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China;Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China;Graduate School of Peking Union Medical College, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China;Key laboratory of big data for spinal deformities, Chinese Academy of Medical Sciences, Beijing, China;Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;School of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China;Key Laboratory of Genomic and Precision Medicine, China Gastrointestinal Cancer Research Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China;University of Chinese Academy of Sciences, Beijing, China;Nanjing Geneseeq Technology Inc., Nanjing, China;PET‐CT Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;School of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China;Translational Medicine Research Institute, Geneseeq Technology Inc., Toronto, ON, Canada;

关键词: cell‐free DNA;    fibroblast growth factor receptor‐1;    mediator complex subunit 12;    next‐generation sequencing;    tumour‐induced osteomalacia;   

DOI  :  10.1111/jcmm.14991

来源: Wiley

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