Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia

Frontiers in Psychology

Lea Kustura¹  Angela Mastelić²  Vana Košta³  Meri Matijaca³  Ana Ćurković Katić³  Ana Proroković⁴  Jelena Vuko⁴  Krešimir Dolić⁵  Ana Poljičanin⁶  Maja Rogić Vidaković⁷  Ana Jerković⁷  Zoran Ðogaš⁸ 

[1] Department Psychiatry, University Hospital of Split, Split, Croatia;Department of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, Croatia;Department of Neurology, University Hospital of Split, Split, Croatia;Department of Psychology, University of Zadar, Zadar, Croatia;Department of Radiology, University Hospital of Split, Split, Croatia;Institute of Physical Medicine and Rehabilitation with Rheumatology, University Hospital of Split, Split, Croatia;Department for Health Studies, University of Split, Split, Croatia;Laboratory for Human and Experimental Neurophysiology, Department of Neuroscience, School of Medicine, University of Split, Split, Croatia;Laboratory for Human and Experimental Neurophysiology, Department of Neuroscience, School of Medicine, University of Split, Split, Croatia;Sleep Medical Center, University of Split, Split, Croatia;

关键词: Hospital Anxiety and Depression Scale (HADS);    psychometrics;    depression;    multiple sclerosis;    anxiety;   

DOI  :  10.3389/fpsyg.2021.794353

来源: Frontiers

【 摘 要 】

Depression and anxiety are common complaints in patients with multiple sclerosis (MS). The study objective was to investigate the factor structure, internal consistency, and correlates of the Croatian version of the Hospital Anxiety and Depression Scale (HADS) in patients with MS. A total of 179 patients with MS and 999 controls were included in the online survey. All subjects completed the HADS and self-administered questionnaires capturing information of demographic, education level, disease-related variables, and the Multiple Sclerosis Impact Scale-29 (MSIS-29). Psychometric properties were examined by estimating the validity, reliability, and factor structure of the HADS in patients with MS. The two HADS subscales (anxiety and depression) had excellent internal consistencies (Cronbach’s α value 0.82–0.83), and factor analysis confirmed a two-factor structure. The convergent validity of the HADS subscales appeared to be good due to the significant correlations between HADS and MSIS-29. Receiver operating characteristic (ROC) analysis indicates that the HADS subscales have a significant diagnostic validity for group differentiation. Hierarchical regression analysis using MSIS-29 subscales as criterion variables showed consistent evidence for the incremental validity of the HADS. The HADS is a reliable and valid self-assessment scale in patients with MS and is suggested to be used in clinical monitoring of the psychiatric and psychological status of patients with MS.

【 授权许可】

CC BY