Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Frontiers in Medicine

Marian Dmochowski¹  Magdalena Jałowska¹  Anna Rosińska-Więckowicz¹  Monika Bowszyc-Dmochowska² 

[1] Autoimmune Blistering Dermatoses Section, Department of Dermatology, Poznan University of Medical Sciences, Poznań, Poland;Cutaneous Histopathology and Immunopathology Section, Department of Dermatology, Poznan University of Medical Sciences, Poznań, Poland;

关键词: bullous pemphigoid;    infants;    autoimmune blistering;    COVID-19;    RT-PCR;   

DOI  :  10.3389/fmed.2021.760823

来源: Frontiers

【 摘 要 】

Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.

【 授权许可】

CC BY