Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Italian Journal of Pediatrics

Marcello Cimador¹  Giovanni Savarino¹  Ingrid Anne Mandy Schierz¹  Maurizio Carta¹  Mario Giuffrè¹  Giovanni Corsello¹  Gregorio Serra¹  Antonio Corsello² 

[1] Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University Hospital “P. Giaccone”, Palermo, Italy;University of Milan, Milan, Italy;

关键词: Necrotizing enterocolitis;    NEC;    Pediatric nutrition;    Neonatology;    Pediatric surgery;    Enteral formulas;    Pediatric gastroenterology;    Very low birth weight infants;    Preterm newborns;   

DOI  :  10.1186/s13052-021-01180-8

来源: Springer

【 摘 要 】

Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.

【 授权许可】

CC BY